吴耐穿越成患癌房东，有四套房产租给白雪、于倩、沙丽丽。他觉醒“惊讶系统”，靠让租客惊讶来治病。他用夸张和机智行为制造惊讶，有许多搞笑感人故事，最终治愈癌症并与租客建立深厚情谊。
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沈玉芷与谢知樾青梅竹马，却被疯帝顾蔚拆散，谢家遭抄。沈玉芷入宫成宠妃，谢知樾怀恨。七年后，已成叛军统领的他闯入皇宫，却不知疯帝觊觎的是沈玉芷骨血，已用其打造玉骨龙椅等他来。
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身价千亿的大小姐谢玲玲竟当街偷窃两盒瑞士卷把自己送进监狱。原来上辈子，张海洋的小青梅沈明月犯下偷东西撞人逃逸的大错，却栽赃到谢玲玲头上，害她被受害者家属捅死，重活一世，谢玲玲决心粉碎二人的阴谋……
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战部传奇“狼王”赵辉，因十年奋战患创伤应激症，看到血或愤怒心率超200就失控，只有抚慰犬光辉能唤醒他。归乡时在江陵街头与权贵陈哲夫妇相撞，对方肆意欺辱，还殴打光辉，赵辉心率突破300，彻底暴走。
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首富收养的女儿陈曦想要寻找亲生父母，路上却和亲生父母的车辆相撞。亲生父亲和弟弟仗着未来能和首富成为亲戚，对陈曦侮辱打骂，却不知道，眼前这个被他们打到濒死的穷丫头，就是他们今天要相认的首富之女。
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周静被前夫以不孕为由休弃，进城工作后意外怀孕，却遭前夫追讨彩礼并污蔑。孩子生父陆成斌知晓后救下周静，周静入住陆家。陆家三姑婆对她关怀备至，陆成斌也对她呵护有加。然而，陆成斌的追求者宋辞辞多次刁难周静，甚至想公开其裸照羞辱她。陆成斌查明真相后严惩宋辞辞，最终周静与陆成斌化解误会，互诉爱意，成功求婚领证，周静顺利产下龙凤胎，一家人幸福美满。
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六皇子萧时卿想为母报仇却发现自己活着都很艰难，因此他主动找到深受皇上信任的九千岁裴淮之合作，相处过程中，萧时卿把裴淮之当成亦师亦友的知己伙伴，但他却不知道，裴淮之的真实身份竟然是前朝太子，他留在宫中的目的就是报仇！！
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宋依依梦到车祸和两个老公，醒来发现出差的老公提前归来，行为怪异，起了疑心。调查后得知老公出车祸有间歇性失忆，本想补偿，却撞破老公与表妹出轨。被迷晕醒来，竟被告知自己是精神病。后来闺蜜查到沈子明有双胞胎弟弟沈子辰，两人心怀不轨，转移财产。宋依依布局复仇，救回孩子。最终摆脱危机，带着孩子离开，而这一切，只是个故事。
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孟奚云六扇门神捕，因揭露官场黑暗被何聂两家追杀。隐姓埋名默默守护家人。王一行联手，欲灭孟氏武馆，引发血战。孟奚云身份暴露，仇敌何聂两家，对孟氏报复。孟奚云凭借高深武艺，一网打尽仇敌，保护家人。
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左蓝是影帝安予初的老婆。安予初答应了帮左蓝的妹妹左小芸上恋综找个好对象。左蓝听从妈妈的遗嘱，从小到大都像个仆人一样照顾着左小芸，然而，左蓝的一片苦心，却被左小芸误会认定是影帝安予初对她有意思。